Metabolic and endocrine characteristics of pregnancy toxemia in the ferret
نویسندگان
چکیده
Metabolic and endocrine characteristics of pregnancy toxemia are well documented in small ruminants, but less known in other species. The objective of this study was to measure plasma levels of certain metabolites and metabolic hormones related to the energetic status in blood from sick and healthy, non-pregnant (control) ferrets. Blood was collected from moribund, hypothermic, late pregnant females suffering from pregnancy toxemia (n = 4) and from healthy female ferrets (n = 14) to measure glucose, ketone (βOH-butyrate, BHB), insulin, thyroxine (T4) and 3,3’,5-triiodothyronine (T3) concentrations. In contrast to healthy animals, hypoglycemia, hyperketonemia, hypoinsulinemia and decreased T4 and T3 levels were detected in females with pregnancy toxemia and necropsy showed excessive hepatic lipidosis. In summary, it can be concluded that pregnancy toxemia caused by a negative energy balance in ferrets resembles the late-gestational hyperketonemia of twin-pregnant ewes, and moreover that similar endocrine changes may occur.
منابع مشابه
Diagnosis, Treatment and Prevention of Pregnancy Toxemia in Ewes
Thin ewes or very over-conditioned ewes and ewes carrying multiple pregnanciesare more likely to develop pregnancy toxemia (ketosis). Pregnancy toxemia is a metabolic disorder characterized by hypoglycemia and hyperketonemia resulting from incapacity of the ewes to maintain adequate energy balance (usually in the last 5-6 weeks).Available information about pregnancy toxemia focuses mainly on pa...
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